Anti-inflammatory tripeptide
The C-terminal tripeptide of alpha-MSH (Lys-Pro-Val), studied in the preclinical literature for its anti-inflammatory and gut-mucosal activity. Supplied as a 10 mg vial, or as a pre-filled research pen in 10 mg, 20 mg and 30 mg.
| Compound | KPV (Lys-Pro-Val) |
| Research category | Regenerative Research |
| Available sizes | Vial: 10 mg · Pen: 10 mg, 20 mg, 30 mg |
| Pricing | Vial £30 · Pen £60 / £85 / £110. Prices exclude postage. |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Tripeptide (alpha-MSH C-terminal fragment) |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.44 g/mol |
| CAS Registry Number | 67727-97-3 |
| Amino acid sequence | Lys-Pro-Val (KPV) |
| Receptor / mechanism | Anti-inflammatory signalling; melanocortin-pathway derived. Refer to primary literature. |
| Reported half-life | Short; small tripeptide rapidly cleared once reconstituted. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 18+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Research compound. Not an approved medicine in the UK. |
KPV is the Lys-Pro-Val tripeptide that forms the C-terminal sequence of the melanocortin alpha-MSH. It is characterised in the preclinical literature (for example Dalmasso et al. 2008 and Kannengiesser et al. 2008) for anti-inflammatory activity in intestinal-epithelial and colitis research models, retaining part of alpha-MSH's activity in a much smaller, more stable fragment. Supplied for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
KPV is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
Every batch of KPV we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with KPV often work alongside the following compounds in the preclinical literature: